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Civica Rx partners with Thermo Fisher Scientific to develop and manufacture drugs with a history of drug shortages

By working with Thermo Fisher to develop Civica-owned Abbreviated New Drug Applications (ANDAs), Civica will secure the manufacture of certain essential medications, further mitigating the risk of drug

The post Civica Rx partners with Thermo Fisher Scientific to develop and manufacture drugs with a history of drug shortages appeared first on Pharmaceutical Business review.


Neuroptika announces enrolment of first patient in phase 2 clinical trial for dry eye disease

NRO-1 is a novel therapeutic with the potential to protect and regenerate corneal nerves in ophthalmic diseases. “Existing treatments for dry eye disease are focused on symptomatic therapy

The post Neuroptika announces enrolment of first patient in phase 2 clinical trial for dry eye disease appeared first on Pharmaceutical Business review.


Merck wraps up $2.7bn acquisition of biopharmaceutical firm ArQule

Via its subsidiary, Merck has completed the cash tender offer to acquire all the outstanding shares of ArQule at a purchase price of $20 per share. Merck said

The post Merck wraps up $2.7bn acquisition of biopharmaceutical firm ArQule appeared first on Pharmaceutical Business review.


FDA accepts for priority review Bristol-Myers Squibb’s application for Opdivo plus Yervoy in first-line NSCLC

The FDA has granted the application Priority Review with a Prescription Drug User Fee Act (PDUFA) goal date of May 15, 2020. “The FDA’s acceptance of our application

The post FDA accepts for priority review Bristol-Myers Squibb’s application for Opdivo plus Yervoy in first-line NSCLC appeared first on Pharmaceutical Business review.


Twist Bioscience announces strategic collaboration with Schrödinger for drug discovery

Under the terms of the agreement, each company will contribute their individual expertise in a highly collaborative manner to discover novel antibody therapeutics. Specifically, Schrödinger will use its

The post Twist Bioscience announces strategic collaboration with Schrödinger for drug discovery appeared first on Pharmaceutical Business review.


ViiV Healthcare secures Japanese approval for Dovato to treat HIV-1 infection

The Japan Ministry of Health, Labour and Welfare (MHLW) has approved Dovato to treat HIV-1 infection in adults and adolescents above12 years of age with a minimum of

The post ViiV Healthcare secures Japanese approval for Dovato to treat HIV-1 infection appeared first on Pharmaceutical Business review.


Astellas, Adaptimmune sign deal to co-develop T-cell therapies for cancer

As per the terms of the deal, the Japanese pharma company and Adaptimmune will select up to three targets for their collaboration and will co-develop T-cell therapy candidates

The post Astellas, Adaptimmune sign deal to co-develop T-cell therapies for cancer appeared first on Pharmaceutical Business review.


BioMotiv and Atomwise sign AI partnership to transform therapeutic development

The organizations will form co-owned, joint development companies (“JDCs”) that will integrate Atomwise’s AI technology and BioMotiv’s deep expertise in preclinical and clinical development to translate innovative academic

The post BioMotiv and Atomwise sign AI partnership to transform therapeutic development appeared first on Pharmaceutical Business review.


Charles River, Takeda announce scientific collaboration to identify and develop preclinical candidates

Together, Charles River and Takeda will launch multiple integrated programs across Takeda’s four core therapeutic areas—oncology, gastroenterology, neuroscience, and rare disease—with the ultimate goal of delivering preclinical candidates

The post Charles River, Takeda announce scientific collaboration to identify and develop preclinical candidates appeared first on Pharmaceutical Business review.


Bayer to commercialise Daré’s monthly contraceptive Ovaprene in US

Ovaprene is Daré’s investigational hormone-free monthly vaginal contraceptive, which is under clinical development to prevent pregnancy. Under the exclusive licence agreement, Bayer will commercialise Ovaprene after it is

The post Bayer to commercialise Daré’s monthly contraceptive Ovaprene in US appeared first on Pharmaceutical Business review.


Drugs.com - News for Health Professionals
Headline news from Drugs.com. Comprehensive and up-to-date drug news for both consumers and healthcare professionals.

Americans Lack Knowledge About Eye Health
FRIDAY, Jan. 17, 2020 -- Americans' lack of knowledge about eye health may put their vision at risk, according to a survey released by the American Academy of Ophthalmology. A total of 3,512 U.S. adults (≥18 years of age) participated in the...
Stomach Virus Strikes 170 Yosemite Visitors, Staff
FRIDAY, Jan. 17, 2020 -- About 170 visitors and employees at Yosemite National Park have been hit by gastrointestinal illness, park officials say. They said most of the cases occurred around the first week of January and the number of new cases has...
Second Death From New Coronavirus Reported in China
FRIDAY, Jan. 17, 2020 -- Chinese officials have reported a second death from a new coronavirus responsible for an outbreak of pneumonia in the city of Wuhan, while the U.S. Centers for Disease Control and Prevention has implemented enhanced health...
FDA Warns of Surgical Gowns That May Not Be Sterile
FRIDAY, Jan. 17, 2020 -- Certain surgical gowns and surgical packs made by Cardinal Health may not be sterile and should not be used, the U.S. Food and Drug Administration said Thursday. On Jan. 11 and Jan. 15, 2020, the medical device maker alerted...
Regional Outreach Boosts Female Residency Recruitment
FRIDAY, Jan. 17, 2020 -- Outreach to female medical students may improve recruitment into orthopedic surgery resident programs, according to a study recently published in the Journal of Surgical Education. Brandon E. Earp, M.D., from Brigham and...
Longer External Ventricular Drain Closures Needed to Read ICP
FRIDAY, Jan. 17, 2020 -- Most external ventricular drain (EVD) closures performed in patients with subarachnoid hemorrhage last less than one minute, and intracranial pressure (ICP) equilibrium is not reached to allow accurate measurement of ICP...
CDC: Benzodiazepines Prescribed at 27 Office Visits Per 100 Adults
FRIDAY, Jan. 17, 2020 -- Benzodiazepines were prescribed at 27 annual physician office visits per 100 adults during 2014 to 2016, according to a study published online Jan. 17 in the National Health Statistics Reports, a publication from the U.S....
Acute Flaccid Myelitis Features Differ in Peak, Nonpeak Years
FRIDAY, Jan. 17, 2020 -- Clinical and laboratory characteristics of acute flaccid myelitis (AFM) cases differ in peak and nonpeak years, according to a study published online Jan. 15 in Emerging Infectious Diseases, a publication of the U.S. Centers...
Quickly Reducing High Potassium Levels Improves Outcomes
FRIDAY, Jan. 17, 2020 -- Rapid correction of elevated serum potassium levels (K+) is associated with reduced mortality in emergency department patients, according to a study recently published in the American Journal of Emergency Medicine. Adam J....
Colorectal Cancer Risk Still Up in Patients With Ulcerative Colitis
FRIDAY, Jan. 17, 2020 -- Patients with ulcerative colitis have an increased risk for colorectal cancer and colorectal cancer mortality, according to a study published in the Jan. 11 issue of The Lancet. Ola Olén, M.D., from the Karolinska...
Lack of Self-Exams Hampers Early Melanoma Identification
FRIDAY, Jan. 17, 2020 -- The biggest obstacle to early detection and treatment of melanoma among residents of rural, frontier communities is a chronic lack of skin self-examination (SSE), according to a study recently published in Psychology, Health...
Level of Antibiotic Prescribing High for Children in Tennessee
FRIDAY, Jan. 17, 2020 -- The outpatient antibiotic prescribing rate for children was 1,165 per 1,000 in Tennessee in 2016, according to a study published online Jan. 15 in Infection Control & Hospital Epidemiology. Sophie E. Katz, M.D., M.P.H.,...
Cancer Survivors Have Substantial Medical Financial Hardship
FRIDAY, Jan. 17, 2020 -- Many cancer survivors have substantial medical financial hardship and make financial sacrifices, according to a study published online Jan. 15 in Cancer Epidemiology, Biomarkers & Prevention. Xuesong Han, Ph.D., from the...
Decline in Mortality Seen in Diabetes Patients in Hong Kong
FRIDAY, Jan. 17, 2020 -- From 2001 to 2016, mortality declined among people with diabetes in Hong Kong, according to a study published online Jan. 16 in Diabetologia. Hongjiang Wu, M.P.H., Ph.D., from the Chinese University of Hong Kong Prince of...
2011 to 2017 Saw Increase in Binge Drinks Per Binge Drinker
FRIDAY, Jan. 17, 2020 -- From 2011 to 2017, there was an increase in the total annual number of binge drinks per adult who reported binge drinking, according to research published in the Jan. 17 issue of the U.S. Centers for Disease Control and...
CDC: Many Americans Are Inactive, With Southerners Faring Worse
THURSDAY, Jan. 16, 2020 -- More than 15 percent of American adults are physically inactive, according to a new U.S. Centers for Disease Control and Prevention study. Today, the agency unveiled new estimates of physical inactivity across states and...
2003 to 2017 Saw Drop in Infant Mortality Due to Birth Defects
THURSDAY, Jan. 16, 2020 -- From 2003 to 2017, there was a decrease in infant mortality attributable to birth defects (IMBD) overall, although considerable differences were seen in the decreases by maternal and infant characteristics, according to...
Single-Payer System Would Likely Save Money
THURSDAY, Jan. 16, 2020 -- There is near consensus across 30 years of economic analysis of single-payer plans that a single-payer system would reduce health expenditures in the United States, according to a review published online Jan. 15 in PLOS...
Sepsis Associated With Almost 20 Percent of Global Deaths
THURSDAY, Jan. 16, 2020 -- From 1990 to 2017, there was a decrease in sepsis incidence and mortality, although considerable regional variation exists, according to a study published online Jan. 16 in The Lancet. Kristina E. Rudd, M.D., from the...
Japan Reports First Case of New Coronavirus
THURSDAY, Jan. 16, 2020 -- Japan has reported its first case of a new coronavirus that has caused an outbreak in China. A Chinese man in his 30s tested positive for the pneumonia-like coronavirus, Japan's Health Ministry said Thursday, The New York...
Increasing Vegetable Intake Does Not Slow Prostate Cancer
THURSDAY, Jan. 16, 2020 -- A behavioral intervention that increases vegetable consumption does not reduce the risk for progression of early-stage prostate cancer, according to a study published in the Jan. 14 issue of the Journal of the American...
Ageism Predicts Significantly Worse Health Outcomes
THURSDAY, Jan. 16, 2020 -- Ageism predicts significantly worse health outcomes, according to a review published online Jan. 15 in PLOS ONE. E-Shien Chang, from Yale School of Public Health in New Haven, Connecticut, and colleagues conducted a...
Cesarean Rates No Higher for Diabetes Patients Induced in 38th Week
THURSDAY, Jan. 16, 2020 -- In women with prepregnancy type 1 and 2 diabetes mellitus (PDM), induction of labor (IOL) is not associated with increased cesarean section rates compared with expectant management beyond 39 weeks, but it is associated...
Popular Diets May Impact Testosterone Levels in Men
THURSDAY, Jan. 16, 2020 -- Men adhering to low-fat diets have lower serum testosterone levels even when adjusting for comorbidities, age, body mass index, and activity levels, according to a study published in the February issue of The Journal of...
ACA Tied to Narrowing of Disparities in Access to Care
THURSDAY, Jan. 16, 2020 -- The Affordable Care Act has reduced disparities in access to health care among black, Hispanic, and white adults, according to a January data brief released by the Commonwealth Fund. Jesse C. Baumgartner, from the...
Satisfaction High With Mohs Surgery for Melanoma In Situ
THURSDAY, Jan. 16, 2020 -- Patients are very satisfied with Mohs micrographic surgery (MMS) for melanoma in situ, according to a research letter recently published in Dermatologic Surgery. Daniel Condie, M.D., from the UT Southwestern Medical Center...
High-Dose Erythropoietin No Benefit for Extreme Preemies
THURSDAY, Jan. 16, 2020 -- For extremely preterm infants, high-dose erythropoietin treatment from 24 hours after birth does not result in a reduced risk for severe neurodevelopmental impairment or death at age 2 years, according to a study published...
Coronary Artery Disease Risk Down in Survivors of Childhood Cancer
THURSDAY, Jan. 16, 2020 -- There has been a decrease in the risk for coronary artery disease among adult survivors of childhood cancer, according to a study published online Jan. 15 in The BMJ. Daniel A. Mulrooney, M.D., from St. Jude Children's...
Lack of Insurance Tied to Later Stage of Breast Cancer at Diagnosis
THURSDAY, Jan. 16, 2020 -- Insurance status and access to care play an important role in racial disparities in stage of breast cancer at diagnosis, according to a study published online Jan. 9 in JAMA Oncology. Naomi Y. Ko, M.D., from the Boston...
History of Falls Predicts Future Fractures in Postmenopausal Women
THURSDAY, Jan. 16, 2020 -- A history of falls, especially injurious falls, predicts subsequent fractures in postmenopausal women, according to a study recently published in Osteoporosis International. Nadia Afrin, M.P.H., from the University of...
2011 to 2017 Saw Increase in Spending on DMTs for MS
WEDNESDAY, Jan. 15, 2020 -- From 2011 to 2017, there was an increase in gross annual expenditures on multiple sclerosis (MS) disease-modifying therapies (DMTs), with increased spending mainly driven by increases in per-prescription costs, according...
Outcomes Superior for HM3 LVAD Regardless of Preimplant Strategy
WEDNESDAY, Jan. 15, 2020 -- For patients with advanced heart failure, the HeartMate 3 (HM3) left ventricular assist device (LVAD) is superior to the HeartMate II (HMII), regardless of whether the device is a bridge to transplant (BTT) or a...
FDA: Weight Control Drug Lorcaserin May Raise Cancer Risk
WEDNESDAY, Jan. 15, 2020 -- The prescription weight control medicine lorcaserin (Belviq, Belviq XR) may increase the risk for cancer, according to the results of a clinical trial assessing the safety of the drug, the U.S. Food and Drug...
New Coronavirus in China Could Possibly Spread Between Humans
WEDNESDAY, Jan. 15, 2020 -- Human-to-human transmission of a virus causing an outbreak in central China may be possible, but the risk appears to be low, health officials said Wednesday. In the city of Wuhan, 41 people have received a preliminary...
CDC: Romaine Lettuce E. Coli Outbreak Over
WEDNESDAY, Jan. 15, 2020 -- It is safe again to buy and eat romaine lettuce grown on farms around Salinas, California, the U.S. Centers for Disease Control and Prevention said Wednesday. The CDC first issued a warning on Nov. 22, 2019, that...
Interventions More Likely After RYGB Versus Sleeve Gastrectomy
WEDNESDAY, Jan. 15, 2020 -- Among adults undergoing bariatric surgery, interventions, operations, and hospitalizations are more likely after Roux en Y gastric bypass (RYGB) than after sleeve gastrectomy (SG), according to a study published online...
Enterovirus A71 Outbreak in Children ID'd in Colorado Hospital
WEDNESDAY, Jan. 15, 2020 -- In an observational cohort study recently published in The Lancet Infectious Diseases, details are presented for an outbreak of enterovirus A71 (EV-A71) neurological disease in children who presented to a Colorado...
Care Management for Complex Needs May Not Cut Readmissions
WEDNESDAY, Jan. 15, 2020 -- Among patients with very high use of health care services, readmission rates were not lower for those assigned to a care-transition program compared with usual care, according to a study published in the Jan. 9 issue of...
BP Measures Progress More Rapidly in Women Than Men
WEDNESDAY, Jan. 15, 2020 -- Blood pressure (BP) measures progress more rapidly in women than in men, starting in the third decade and continuing through the life course, according to a study published online Jan. 15 in JAMA Cardiology. Hongwei Ji,...
Online Information About Probiotics Often Unreliable
WEDNESDAY, Jan. 15, 2020 -- Probiotics information available online is often from commercial sources, and most webpages do not refer to scientific literature, according to a study published online Jan. 15 in Frontiers in Medicine. Marie Neunez, from...

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