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Grifols secures FTC’s conditional approval for Biotest US acquisition

Grifols is a global healthcare company based in Spain. Biotest US is a healthcare company based in Florida. According to the complaint, which was announced in August 2018,

The post Grifols secures FTC’s conditional approval for Biotest US acquisition appeared first on Pharma Business review.


Norgine to commercialize Shield’s iron deficiency therapy in Europe, Australia and New Zealand

Under the terms of the agreement, Shield will receive an immediate £11 million upfront payment, is eligible to receive up to €4.5m in short-term development milestones and up

The post Norgine to commercialize Shield’s iron deficiency therapy in Europe, Australia and New Zealand appeared first on Pharma Business review.


ACCC clears merger of generic pharmaceutical firms Arrow and Apotex

The ACCC promotes competition and fair trade in markets to benefit consumers, businesses, and the community. ​In May this year, Apotex Australia announced a merger of their Australian

The post ACCC clears merger of generic pharmaceutical firms Arrow and Apotex appeared first on Pharma Business review.


Zealand’s dasiglucagon succeeds in phase 3 trial for severe hypoglycemia

Dasiglucagon is a potential first-in-class soluble glucagon analog invented and developed by Zealand. It is in development in the ready-to-use HypoPal rescue pen for easy, fast and effective

The post Zealand’s dasiglucagon succeeds in phase 3 trial for severe hypoglycemia appeared first on Pharma Business review.


BeiGene selects GE’s KUBio facility to boost cancer drugs manufacturing capacity

The KUBio biomanufacturing facility for BeiGene will be located in Guangzhou in the Chinese province Guangdong, where other biotech firms are setting up operations, said GE. It will

The post BeiGene selects GE’s KUBio facility to boost cancer drugs manufacturing capacity appeared first on Pharma Business review.


Cancer Genetics, NovellusDx agree to merge

Cancer Genetics will be the surviving entity and expects to remain listed on the Nasdaq Stock Market. This transaction will combine Cancer Genetics’ scale, expansive test portfolio and

The post Cancer Genetics, NovellusDx agree to merge appeared first on Pharma Business review.


Novo Nordisk to slash 400 jobs in R&D restructuring

The company is restructuring its R&D organization to accelerate the expansion and diversification of its pipeline across severe chronic diseases, in addition to supporting increased investment in transformational

The post Novo Nordisk to slash 400 jobs in R&D restructuring appeared first on Pharma Business review.


Cellectar gets FDA rare pediatric disease designation for CLR 131 to treat osteosarcoma

The CLR 131 is an investigational radioiodinated PDC therapy, which exploits the tumor-targeting properties of the firm’s phospholipid ether (PLE) and PLE analogs to selectively deliver radiation to

The post Cellectar gets FDA rare pediatric disease designation for CLR 131 to treat osteosarcoma appeared first on Pharma Business review.


Roivant launches biopharmaceutical firm to develop therapeutics for respiratory diseases

Respivant will be led by chief executive officer Bill Gerhart, Executive Vice President for Clinical and Regulatory Ahmet Tutuncu, MD, PhD, and Executive Vice President for Development and

The post Roivant launches biopharmaceutical firm to develop therapeutics for respiratory diseases appeared first on Pharma Business review.


Pfizer to evaluate Atomwise’s platform to identify drug candidates for three target proteins

Pfizer will evaluate Atomwise’s platform to identify potential drug candidates for up to three target proteins selected by Pfizer. In the agreement, Pfizer will pay a technology access

The post Pfizer to evaluate Atomwise’s platform to identify drug candidates for three target proteins appeared first on Pharma Business review.




Drugs.com - News for Health Professionals
Headline news from Drugs.com. Comprehensive and up-to-date drug news for both consumers and healthcare professionals.

Patient-Directed IV Remifentanil Cuts Epidural Conversions
WEDNESDAY, Sept. 19, 2018 -- Compared with intramuscular pethidine, use of intravenous remifentanil patient-controlled analgesia (PCA) in labor reduces the proportion of epidural conversions, according to a study published in the Aug. 25 issue of...
California Lawsuit Claims AbbVie Paid Doctors to Prescribe Humira
WEDNESDAY, Sept. 19, 2018 -- A lawsuit filed Tuesday in California claims that pharmaceutical company AbbVie used cash, gifts, and services to induce doctors to overprescribe the widely used drug Humira (adalimumab), ignoring the medicine's...
Medicaid Expansion Linked to Gains in Insurance Coverage
WEDNESDAY, Sept. 19, 2018 -- Medicaid expansion was associated with gains in insurance among low-income adults with substance use disorders, but corresponding treatment gains were not seen, according to a study published in the August issue of...
No Clear Benefit for Rivaroxaban After Hospital Discharge
WEDNESDAY, Sept. 19, 2018 -- Rivaroxaban does not lower risk of symptomatic venous thromboembolism and related death in medical patients after hospital discharge, compared to placebo, according to a study published in the Sept. 20 issue of the New...
Pediatricians Have Role in Supporting Transgender Youth
WEDNESDAY, Sept. 19, 2018 -- In an American Academy of Pediatrics policy statement published online Sept. 17 in Pediatrics, recommendations are presented to ensure comprehensive care and support for youth who identify as transgender and gender...
EPA Plan Will Maintain Carbon Emissions From Power Plants
WEDNESDAY, Sept. 19, 2018 -- The U.S. Environmental Protection Agency (EPA) has formally released its proposal to replace the Clean Power Plan with the Affordable Clean Energy Rule, which will keep carbon emissions from power plants constant,...
Second HPV-Related Primary Cancers Common in Survivors
WEDNESDAY, Sept. 19, 2018 -- The risk of human papillomavirus-associated second primary cancers (HPV-SPCs) among survivors of HPV-associated cancers is significant, according to a study published online Sept. 7 in JAMA Network Open. Ryan Suk, from...
HTN Tx Intensification Common Upon Discharge in U.S. Vets
WEDNESDAY, Sept. 19, 2018 -- Fourteen percent of older adults hospitalized with non-cardiac conditions are discharged with intensified antihypertensive treatment, of whom more than half had previously well-controlled outpatient blood pressure,...
Patient Health Information Often Shared Electronically
WEDNESDAY, Sept. 19, 2018 -- The most common electronically sent and received types of patient health information (PHI) include laboratory results and medication lists, according to a report published Aug. 15 by the U.S. Centers for Disease Control...
Global Prevalence of Insufficient Activity 27.5 Percent
WEDNESDAY, Sept. 19, 2018 -- In 2016 the age-standardized prevalence of insufficient physical activity was 27.5 percent, according to a study published in the October issue of The Lancet Global Health. Regina Guthold, Ph.D., from the World Health...
20% of Children, Adolescents Use Prescription Medications
WEDNESDAY, Sept. 19, 2018 -- Almost 20 percent of children and adolescents used prescription medications in 2013 to 2014, and 8.2 percent of concurrent users of prescription medications in 2009 to 2014 were at risk for a potentially major drug-drug...
Quarterly Canakinumab Reduces Risk for Gout Attacks
WEDNESDAY, Sept. 19, 2018 -- Quarterly canakinumab administration is associated with significantly reduced risk for gout attacks without any change in serum uric acid levels, according to a study published online Sept. 18 in the Annals of Internal...
USPSTF Recommends Intensive Behavioral Change for Obesity
WEDNESDAY, Sept. 19, 2018 -- Primary care physicians should offer or refer obese patients to intensive behavioral interventions, according to a U.S. Preventive Services Task Force (USPSTF) final recommendation statement published in the Sept. 18...
Opioid Deaths 1999 to 2015 May Be Dramatically Underestimated
WEDNESDAY, Sept. 19, 2018 -- States may be greatly underestimating the effect of opioid-related overdose deaths because of incomplete cause-of-death reporting, according to a study recently published in Public Health Reports. Jeanine M. Buchanich,...
Cardiac MR With Contrast Feasible in Developing World
WEDNESDAY, Sept. 19, 2018 -- A cardiac magnetic resonance (CMR) with contrast protocol is feasible for implementation in the developing world and can impact management, according to a study published in the Sept. 4 issue of the Journal of the...
FDA takes important steps to encourage appropriate and rational prescribing of opioids through final approval of new safety measures governing the use of immediate-release opioid analgesic medications
September 18, 2018 -- Today, the U.S. Food and Drug Administration took new steps as part of its broader efforts to address the opioid crisis by approving the final Opioid Analgesic Risk Evaluation and Mitigation Strategy (REMS). This new plan...
Socioeconomic Status Lower Among U.S. Sexual Minorities
TUESDAY, Sept. 18, 2018 -- Sexual minorities, especially females, are of lower socioeconomic status (SES) than their heterosexual counterparts, according to a study published online Sept. 6 in the Journal of Epidemiology & Community...
Sport Specialization Tied to Pediatric Overuse Injury
TUESDAY, Sept. 18, 2018 -- Sport specialization in children and adolescents is associated with an increased risk of overuse musculoskeletal injuries, according to a review published in the September issue of Pediatrics. David R. Bell, Ph.D., from...
U.S. Senate Passes Opioids Bill
TUESDAY, Sept. 18, 2018 -- The Senate on Monday passed on a 99-1 vote legislation aimed at curbing the nation's ongoing opioid addiction crisis. The comprehensive bipartisan package earmarks billions of dollars to prevent cross-border opioid...
FDA Ad Campaign Hopes to Halt E-Cigarette Use Among Teens
TUESDAY, Sept. 18, 2018 -- The U.S. Food and Drug Administration on Tuesday launched a new ad campaign aimed at curbing rampant e-cigarette use among American teens. The new program, called "The Real Cost" Youth E-Cigarette Prevention Campaign, is...
Active Choice Intervention Tied to Increase in Flu Shot Rates
TUESDAY, Sept. 18, 2018 -- An active choice intervention is associated with an increase in influenza vaccination rates, according to a study published online Sept. 14 in JAMA Network Open. Rebecca H. Kim, M.D., M.P.H., from the University of...
Drug Prices Increase More Than Expected After Shortages
TUESDAY, Sept. 18, 2018 -- Prices for drugs under shortage increase more than twice as quickly as expected in the absence of a shortage, according to a research letter published online Sept. 18 in the Annals of Internal Medicine. Inmaculada...
Scribes Improve Physician Workflow, Patient Interaction
TUESDAY, Sept. 18, 2018 -- Use of medical scribes is associated with decreased physician documentation burden, improved work efficiency, and improved patient interactions, according to a study published online Sept. 17 in JAMA Internal...
Incident Contrast Sensitivity Common in Middle-Aged Adults
TUESDAY, Sept. 18, 2018 -- The risk of incident contrast sensitivity (CS) impairment is increased with factors such as cadmium exposure and older age, according to a study published online Sept. 13 in JAMA Ophthalmology. Adam J. Paulsen, from the...
2006 to 2015 Saw Increase in Severe Maternal Morbidity
TUESDAY, Sept. 18, 2018 -- From 2006 to 2015, the proportion of women experiencing severe maternal morbidity increased 45 percent, according to a statistical brief published by the Agency for Healthcare Research and Quality. Kathryn R. Fingar,...
Many Middle, High Schoolers Report E-Cigarette Cannabis Use
TUESDAY, Sept. 18, 2018 -- Nearly one in 11 U.S. middle and high school students used cannabis in electronic cigarettes (e-cigarettes) in 2016, according to a research letter published online Sept. 17 in JAMA Pediatrics. Katrina F. Trivers, Ph.D.,...
Review: Treatments for Primary Basal Cell Carcinoma Compared
TUESDAY, Sept. 18, 2018 -- For patients with primary basal cell carcinoma (BCC), estimated recurrence rates are similarly low for excision, Mohs surgery, curettage and diathermy, and external-beam radiation, according to a review and meta-analysis...
Compliance With Requirement to Report Results on EUCTR Is Poor
TUESDAY, Sept. 18, 2018 -- Half of trials on the European Union Clinical Trials Register (EUCTR) are non-compliant with the European Commission's requirement that all trials post results to the registry within 12 month of completion, according to a...
Tips for Advising Patients Living in Highly Polluted Settings
TUESDAY, Sept. 18, 2018 -- Clinicians advising families living overseas in highly polluted settings should understand their patients' concerns and have a network of resources to draw upon for guidance, according to an article published in the Aug. 1...
Tafamidis Treats Transthyretin Amyloid Cardiomyopathy
TUESDAY, Sept. 18, 2018 -- In patients with transthyretin amyloid cardiomyopathy, treatment with tafamidis reduces all-cause mortality and cardiovascular-related hospitalizations versus placebo, according to a study published in the Sept. 13 issue...
Ranolazine Doesn't Cut VT, VF, Death in High-Risk ICD Patients
TUESDAY, Sept. 18, 2018 -- For high-risk patients with implantable cardioverter-defibrillators (ICDs), ranolazine does not significantly reduce the risk of ventricular tachycardia (VT) or ventricular fibrillation (VF) requiring appropriate ICD...
FDA Approves Device for Acute Coronary Artery Perforations
MONDAY, Sept. 17, 2018 -- The PK Papyrus Covered Coronary Stent System has been approved by the U.S. Food and Drug Administration to treat acute coronary artery perforations. "An acute coronary artery perforation is a rare, but potentially...
Factors Predictive of Escalated Care in Infant Bronchiolitis ID'd
MONDAY, Sept. 17, 2018 -- Variables have been identified that predict escalated care for infants with bronchiolitis, according to a study published in the September issue of Pediatrics. Gabrielle Freire, M.D., from the University of Toronto, and...
Many Foster Kids Inappropriately Prescribed Psychiatric Drugs
MONDAY, Sept. 17, 2018 -- A new report finds that foster children are often given powerful psychiatric medicines without regard for proper safeguards. The report, coming from the inspector general's office at the U.S. Department of Health and Human...
Proportion of Female Authors Rising in Cardiology Literature
MONDAY, Sept. 17, 2018 -- Over the last two decades, the proportion of women in the first and senior authorship positions has increased in academic cardiology literature, according to an article published in the Aug. 7 issue of the Journal of the...
Decrease in Infant Walker-Related Injuries Since 2010
MONDAY, Sept. 17, 2018 -- Following implementation of a federal mandatory safety standard on infant walkers in 2010, there was a decrease in the number of infant walker-related injuries, according to a study published online Sept. 17 in...
Potentially Inappropriate Opioid Prescribing Tied to Overdose
MONDAY, Sept. 17, 2018 -- Potentially inappropriate prescribing (PIP) of opioids is associated with increased risk of all-cause mortality and fatal and nonfatal overdose, according to a study published in the September issue of the Journal of...
Use of Aspirin in Healthy Elderly Questioned in Three Studies
MONDAY, Sept. 17, 2018 -- Low-dose aspirin appears to have limited effect on healthy life span in older people, according to three studies published online Sept. 16 in the New England Journal of Medicine. John J. McNeil, M.B., B.S., Ph.D., from...
Drug Prices Seem Not to Be Influenced by Their Value
MONDAY, Sept. 17, 2018 -- For commonly prescribed cardiovascular drugs, there is no evidence that drug prices are influenced by their value, according to a study published in the August issue of Health Affairs. Jonathan D. Campbell, Ph.D., from the...
Ambient Particulate Matter Linked to Emergency Asthma Care
MONDAY, Sept. 17, 2018 -- Ambient particulate matter concentrations are associated with emergency/urgent care visits among individuals with asthma, according to a study published in the Aug. 1 issue of the Annals of the American Thoracic...

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